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Dr. Pickart's Peptides mimic natural moisturizing factors that reduce the look of neck creases and sun damage*. Pair with our powerful, cost-effective exfoliators to reduce the appearance of neck sag (or crepey neck skin) to visibly firm the look of your skin*, so that your profile becomes more youthful-looking. Skin is left smoother and softer with velvety texture*.

STEP 1: Select a copper peptide based on your skin type. Dry skin types should use creams / Oily-to-combination skin types can use serums. All of our formulas use leading technology to firm, tone, and improve elasticity*. GHK is a safe copper peptide complex found naturally in human plasma which helps to boost skin's own collagen production.

STEP 2. Select a hydroxy acid exfoliator. Our affordable line of exfoliators refine and resurface skin, reducing skin dullness and minimizing pores.

STEP 3. Enhance with a moisturizer or DMAE. The following skin oils are appropriate for sensitive skin as well as for everyday use. DMAE helps to safely tighten and tone skin*.

Basic Regimen

Start with either Perfect Lift Time Remedy Cream or CP Serum. Or address advanced skin concerns with the stronger GHK-Cu Crepey Skin Escape Cream. Apply a light layer in the morning.

Best Crepey Skin Cream


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CP Serum


Protect and Restore for Breasts Nipples and Decolletage









Choose from LacSal Cream or LacSal Serum (both are 10% hydroxy acid leave-on exfoliators). Apply a light layer in the evening.

LacSal Serum


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LacSal Cream


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Advanced Regimen

Substitute your morning copper peptide with a specialized product (3% GHK VIP Luxury Serum or 3% GHK VIP Luxury Cream) containing a heightened concentration of copper peptides.

3% GHK VIP Luxury Serum

3% GHK VIP Serum

3% GHK VIP Luxury Cream

3% GHK VIP Cream










GHK MSM serum


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OR enhance your results with GHK+MSM Skin Smoothing & Soothing Serum. Proprietary blend of GHK-Cu (proven anti-aging powerhouse) + skin-healthy antioxidants.









Enhance with a light layer of our DMAE quick-firming agent OR our best selling Emu Oil-S for Skin.

Two Timing Tightener 2X Extra Strength Serum


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Emu Oil S for Skin


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*Disclaimer: This statement is not a guarantee of results. Results may vary. Testimonials found on this site are only examples of what some of our clients have reported. We cannot guarantee similar results as every situation is different.



Testimonials from Clients


Copper Peptide Reviews Before After Photos

Copper Peptide Reviews Before After Photos

April 5th, 2019:
Here's an update about the skin on my neck. I used the Squalane Oil for two days and my skin was improving, but it became very dry and itchy. So I did more research on the Skin Biology site and saw that the Super GHK Cream works well on irritated skin. Yesterday morning, after cleansing with Dr. Pickart's soap bar, I smoothed some of the cream on my neck and applied some Squalane Oil over it for better absorption. Not only did the combination help the dryness, but the irritation and itchiness reduced dramatically. Now I'm using the application of the cream and oil day and night. The irritation is not completely gone, but it's improving very nicely. I'm so excited! Using these products means that I will no longer need to use other creams which may weaken the skin. I'm taking pictures of the progress and will send them to you once my neck has been restored.

April 8th:
Here's an update regarding my skin. The irritation on my neck has gotten MUCH better in the front, but the rash is still on both sides of my neck. Because of this, I still wash my neck as normal but starting tonight, I'm dabbing hydrogen peroxide on the area and smooth it with Gold Bond Medicated Baby Powder. However, in the morning, I'll return to using the Super GHK Cream with Squalane over it. Regarding the LacSal Serum usage...when applying the serum to my skin, the raised skin is gone and the small bumps are reduced. There's no itching whatsoever. All these problems stem from having used that Triamcinolone Cream for years which thinned my face and neck skin. I just hope I'm not too late to repair the damage I've done.

April 14th:
The rash on my neck looks so much better thanks to the "Skin Soothing Serum". Yay! I still have some texture irregularities, but over all it looks much better. I'm so thankful to give this item a try. I have been using the Soothing and Smoothing Serum for almost a week and that rapidly helped my neck skin. The bumps and tenderness are no longer there, only dark dry patches are left behind. That serum is wonderful by the way.

April 22nd:
I have some great news. The rash on my neck has dramatically improved using Dr. Pickart's products. Yay! I'll send you the pictures of the entire process later on today. The products I used were as follows:

--- Disinfected area with 3% hydrogen peroxide at night for three days.
--- Followed using the Soothing and Smoothing Serum or GHK-Cu Cream (twice a day then once a day alternating the products).
--- For moisturizing: Squalane Oil and Emu Oil (as needed)
--- For mild exfoliation: Exfol Cream, nightly (this cream didn't irritate my neck in the least. Love it!)

Thank you Dr. Pickart for saving my skin and making wonderful products. I definitely will be ordering more in the future. Forever grateful and follower for life,


I use GHK-Cu Crepey Skin Escape three times a week on my neck with exceptional results! I wish you and Dr. Pickart best wishes for a wonderful 2020. Thanks for giving me new skin and restoring confidence in cosmetics.

- S.T.*
*Disclaimer: Similar results are not guaranteed.

I want to let you know how much better my skin looks since using copper peptides, and thank you for the recommendations for my skin type. The Super Cop has made an amazing difference to deep melasma down both sides on my neck, and I’ve tried many products - yours works.

- S.G.*
*Disclaimer: Similar results are not guaranteed.

OMG ... I love your new Crepey skin product!! I am 57 and have been using it for about 3 weeks. Skin on my forearms looks less crepey! Yay! My problem is that I want to use it everywhere... Always love your products!!


Thank you again for providing such incredible products. I live and work in Beverly Hills (one of the most aesthetically driven places on Earth, LOL) and have been receiving many compliments on my skin. I happily provide them your website and my glowing recommendations. Thanks for keeping so many people radiant and happy.

T, California

This product [GHK-Cu Crepey Skin Escape] works, and it works fast. I am using it on my arms and legs, and have seen about 60% improvement in both feel and appearance just a week. Before using this product, the skin had a map-like quality, will all kinds of fine crinkles. It looked cracked, just as clay soil that has baked in the summer sun looks. I was using all kinds of scrubs and oils, to no avail. I look forward to seeing the results after a month. I am 63.

-Best, G. Your Loyal Customer
*Disclaimer: Similar results are not guaranteed.

Thank you for creating the best products I have ever tried in 40 yrs. I am a make-up artist and have tried most of the high end products from around the world and I can honestly say nothing performs as well as your products.

I'm 57 yrs old and before I started using your products my face looked tired, dull, with loose facial skin . The lines around my eyes looked crepey and my neck started to look like a turkeys neck - not attractive! My baby fine short dry hair never grew as the ends would break. Eeeek, I hated looking in the mirror!

My friends recommended your products and after their rave reviews I took the plunge! :-)

My first order was 5 August 2012 and I bought the P&R Classic, Exfol, Two Timing Tightener and the Super GHK. For my hair I bought Folligen Therapy, Shampoo and Conditioner.

I used the P&R Classic on my face in the morning, Super GHK around my eyes followed by Two Timing Tightener all over.

Evening after cleansing I used Exfol and Squalane (this is an oil I have used for years and had this oil on hand).

I have now been using all of the above products for 8 months and can honestly say I'm looking fabulous! My skin looks hydrated, brighter, plumper and firmer. My hair is softer, looks fuller and doesnt break off at the ends. It's amazing! My friends have all commented that I look younger and they're right. ;-)

I'm truly grateful for all your hard work Dr. Pickart and please know I am a very satisfied customer.

*Disclaimer: Similar results are not guaranteed.

I'm 49 with the usual vertical lines beside the mouth, sagging and some wrinkles at face and neck. I started two months ago with Skin Signals Solution, Two Timing Tightener and Emu Oil Skin. Believe me, I've noticed improvement on all those areas. A friend asked me what I was using, because she noticed how good my neck looks.

S from Florida
*Disclaimer: Similar results are not guaranteed.

For a month now, I've been using the CP serum during the day, and the Exfol Serum at night. Also using the Skin Signals on my neck, where I have had the beginnings of the "turkey neck"... The results since beginning the CP routine are that my face overall looks fresher and more toned. It looks healthier and like I'm well rested... But I would say that the effects of the CP/exfoliation routine are visible and noticeable and I'm happy about that.

*Disclaimer: Similar results are not guaranteed.

I've really noticed considerable lifting of the whole eye area. It's wonderful! Thank you.

*Disclaimer: Similar results are not guaranteed.

I really like this product - it has a wonderful, silky texture - and at the same good effect on my skin. I have noticed real improvement in the neckline area that is exposed to the sun by the cut of sweaters and blouses.

LA, California
*Disclaimer: Similar results are not guaranteed.

Update: I have 'mature' skin ...I am 52. I have been using Skin Bio products and worked up from CP Serum to Super CP serum on my face, neck and upper arms in the late fall ...I believe that the texture of my face and neck has greatly improved. I LOVE the Super CP Serum and my skin seems to tolerate it well. The Squalane with Retinol is the best overall moisturizer that I have ever used on my face, and my face feels much softer than it has been in years.

*Disclaimer: Similar results are not guaranteed.

Define the Look of Your Neck Skin

The beauty of Copper Peptides is their ability to safely supply nutritional copper to the skin for additional support, making copper peptides an effective product for a firmer, lifted neck with a more sculpted look*.

The appearance of sagging neck skin, crepey neck skin, or hyperpigmented neck skin can be improved with the use of Super GHK-Copper Cream, TriReduction Cream, CP Serum, or GHK+MSM Skin Smoothing & Soothing Serum in the morning and Exfol Cream or LacSal Cream in the evening. Or use Perfect Lift Cream to help eliminate excess fullness and volume and gently enhance skin's moisture and firmness.


If you have very sensitive skin, always start with our mildest copper peptide: Super GHK-Copper Cream.


Typical results take approximately 4-6 weeks of consistent use.


Contact a Skin Biology representative at 1 800 405 1912 for further help.