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Using SRCPs for Scalp and Hair
Quick Shop:
• ORDER Folligen Cream or
Folligen Lotion
• ORDER Folligen Plus
Minoxdil Combo
• ORDER Folligen Shampoo
and Folligen Conditioner
• ORDER New Hair Signals
Therapy Solution
• ORDER New Hair Signals
Therapy Cream
• ORDER Folligen Total
Therapy Trial Kit
Natural Multiple Stimulators - Folligen is an advanced version of earlier work on copper-peptides and hair follicle regeneration. Research on skin and hair follicle renewal indicates that optimal regeneration is obtained only when there are multiple signals for renewal. Folligen contains copper ion plus a mixture of numerous different peptides fragments that are generated by natural proteolytic enzymes (as happens after follicle or scalp damage). This produces numerous copper-peptide complexes in a more natural manner to assist the hair's natural regenerative processes.
Rebuilds Protective Acid Mantle - Folligen rebuilds the protective acid mantle of the scalp that shampoos and conditioners remove. The acid mantle is the combination of sebum (oils) and perspiration, on the skin's surface that protects the skin and renders the skin less vulnerable to damage and attack by environmental factors such as sun and wind and less prone to dehydration. The mantle also has strong anti-oxidant properties and is itself oxidized to protect the skin from oxidation. Sebum is naturally white but air oxidation turns it black (this is why "whitehead comedos" turn into "blackhead comedos").
Normal skin and scalp pH is somewhat acid and in the range of 4.2. to 5.6. It varies from one part of the body to another and, in general, the pH of a man's skin is lower (more acid) than that of a woman's. The acid mantle inhibits the growth of foreign bacteria and fungi and the skin remains healthier, and has fewer blemishes. Acne, allergies and other skin problems become more severe when the skin become more alkaline.
Folligen adjusts the scalp pH into the acid range of optimal scalp health at about pH 5.0. Folligen also contains high levels of lipids such as squalane, cetyl alcohol, glyceryl stearate and stearic acid that closely resembles the fats of the acid mantle. Furthermore, Folligen contains antioxidants such as allantoin, aloe, vitamin E and retinol to aid the mantles protective anti-oxidant properties. In this manner, Folligen improves scalp health and aids hair growth. Folligen works well with Minoxidil or the Minoxidil and Retinoic Acid combination.
Safety of Folligen
Folligen has passed numerous safety tests at the University of California at San Francisco (UCSF) and at the Shanghai Medical University. Folligen has been found to be non-irritating and safe. Folligen (1) was non-irritating by the human patch test (5 days of heavy covering of product on the skin), (2) was non-irritating on tape-stripped (injured) human skin, (3) passed the Ames (bacterial) test for carcinogenicity, (4) passed the guinea pig acute skin irritation test and was classified as a non-irritant, (5) passed the human induced-allergy test and classified as a non-allergen, (6) was non-comedogenic in humans and (7) was found have no evidence of oral toxicity in mice.
How Long Will Folligen Last?
A tube of Folligen Cream or Lotion, used 4 times per week, should last about 45 days depending on the size of application area. In our clinical studies, we apply a very light coating (approximately 10 milligrams per square centimeter) to the skin which is then further rubbed into the skin. Folligen Therapy Spray should last 2 to 3 months.
Calming Actions of Folligen on an Irritated Scalp
Folligen often calms irritated scalp tissue that has been irritated with other hair growth stimulator such as minoxidil or retinoic acid. When using Folligen for scalp calming, start with very light applications of Folligen. On a very irritated scalp, even Folligen can cause a brief stinging, but as your scalp repairs itself, it will become more protective and less sensitive to irritation by minoxidil, retinoic acid, or other items.
Can Folligen Cause Scalp Irritation?
We receive very few reports of scalp irritation. But because any person can have a specific allergy to some ingredient, we recommend starting slowly. Published studies on the copper peptides in Folligen found them to have anti-inflammatory properties on human skin. Occasionally, we have been told of reports of scalp irritation by Folligen that are posted on Internet chat sites. Such reports are very periodic and seem to arise in batches when the time other companies are preparing to mass market competing types of copper peptides. About 18 months ago, there was such a batch of postings of irritation by Folligen but not one complaint had been received by Skin Biology. The net effect of these postings was a significant and lasting increase in Folligen sales. Since more mass marketing campaigns are starting, we expect more such postings.
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Cautions:
Heavily bleached, very blond hair may pick up a green tint if Folligen is in contact with the hair. Try to keep the products on the scalp. However, many men and women with blond hair report excellent results with the Folligen products. This is similar to the greenish-tint that may occur after spending time in swimming pools.
Improving Hair Follicle Health for Better Hair Growth - Helping Your Body's Natural Follicle Repair System - Safe, Effective, Scientific
Folligen products for men are either used alone or with other hair stimulating products such as Emu Oil, minoxidil, Propecia and other DHT inhibitors, and retinoic acid. Folligen is compatible with these products and helps improve hair follicle health, reduce DHT, and calm the scalp irritation is sometimes caused by some products. The Folligen products are based on Dr. Pickart's second generation SRCPs - his first generation inventions produced Tricomin and GraftCyte.
All Folligen products contain a high concentration of blue-colored skin remodeling copper-peptide complexes and do not contain any blue dyes or scalp damaging detergents or alcohol. Folligen Solution Therapy Spray uses small amounts of polysorbate 20 and propylene glycol to enhance the uptake of copper-peptide around the hair follicle.
Folligen® aids hair health by helping the scalp tissue repair itself (such as with seborrheic dermatitis or damage from harsh chemicals, sunburn, and hair dryers). Clinical tests of Folligen's key ingredients have demonstrated that the primary effect is to help the skin improve it's barrier function.
Men
Best in age 25 to 45 group
Works well with minoxidil and retinoic acid
Hair shedding often stops within one month
Some report significant hair re-growth after about 4 months
Users report hair shafts look thicker
Often reduces itching and flaking associated with scalp inflammation.
Women
Best in age 40 to 70 group
Hair shedding often stops within one month
Hair shafts are often thicker
Some report strong hair re-growth
Often reduces itching and flaking associated with scalp inflammation.
Patents and Cost - Folligen vs. Graftcyte® and Tricomin®
Folligen Cream, Folligen Lotion, and Folligen Spray
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Tricomin products and Graftcyte products |
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Patents on Technology |
Pickart, US 5,554,375: Tissue protective and regenerative compositions |
Pickart, US 5,550,183 Metal-peptide compositions and methods for stimulating hair growth. Pickart, US 5,214,032 New glycyl-histidyl-lysyl copper compounds used in stimulating hair growth. Pickart, US 5,177,061 Compositions for stimulating hair growth containing cupric complexes of peptide derivatives including. glycyl-l- histidyl-l-lysine n-octyl ester. Pickart, US 5,120,831 New metal peptide complexes and derivatives used for stimulating growth of hair in warm-blooded animals, especially humans. |
Cost |
Folligen Spray - $38.95 for 8oz. / Folligen Cream or Lotion - $21.95 for 2oz |
Tricomin Spray - $48.00 for 6oz / Graftcyte Solution - $70.00 for 4oz
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